In nucleophilic aromatic substitution, the attacking species (the nucleophile) necessarily is negatively charged .
A nucleophilic aromatic substitution is a substitution reaction in organic chemistry in which the nucleophile displaces a good leaving group, such as a halide, on an aromatic ring. Aromatic rings are usually nucleophilic, but some aromatic compounds do undergo nucleophilic substitution.
OH, –OR, –NH2, –SR, NH3, and other amines are nucleophiles that generally show nucleophilic aromatic substitution. Alike SN1 or SN2 greater the halogen atoms electronegativity, the more readily it will leave.
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