The zona pellucida is the region between the developing oocyte and the granulosa cells.
A mammalian ovum's zona pellucida, which is made of glycoproteins, is the translucent, more or less elastic, noncellular outer layer or envelope. Glycoproteins are in charge of sperm's species-specific attachment to unfertilized eggs, the induction of acrosomal exocytosis in sperm, and the inhibition of sperm attachment to fertilized eggs.
The glycoprotein layer known as the zona pellucida covers the mammalian oocytes. The corona radiata and the oocyte plasma membrane are separated by a zone called the zona pellucida. The zona pellucida is crucial for effective fertilization because it triggers the acrosome reaction, which allows sperm to enter the secondary oocyte.
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