NCBI staff started transitioning to Accession-Based BLAST in December 2018. The new system includes of a new version of BLAST+ executables that runs against newly-created accession-based BLAST databases.
In contrast to the traditional BLAST databases that operate on the GeneInfo identifiers (GIs), the new databases use accession numbers as the only type of record identifiers.
Accession-Based BLAST stems from the NCBI-wide activity of phasing out of GIs in the sequences databases. We are now maintaining an increasing number of sequence records that no longer contain GIs as their secondary identifiers. While we are unable to include such records in the traditional BLAST databases, the new system allows us to do so.
What is accession number?
Accession number (bioinformatics), a unique identifier given to a biological polymer sequence (DNA, protein) when it is submitted to a sequence database.
What is blast?
The Basic Local Alignment Search Tool (BLAST) is an algorithm and program that finds the region of local similarity between the sequences by the comparison of the primary biological sequence information of amino acids found in proteins or the nucleotides of DNA or RNA sequences.
Learn more about blast results here:
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