Compare the difference between the bar-headed goose high altitude hemoglobin and the graylag goose hemoglobin, to the difference between human hemoglobin in the lungs and in the body. Do you see similarities in how high and low affinity forms differ in structure?.

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Answer: The hemoglobin of bar-headed geese has a higher affinity for O2 (whole-blood P50 of 4.0 kPa at pH 7.4 and CO2 tension of ∼5 kPa) than that of closely related lowland geese (5.3 kPa in greylag goose under the same conditions) (32), which increases pulmonary O2 loading and peripheral O2 delivery in hypoxia by increasing. Bar-headed geese have several adaptions that help them exercise in low oxygen conditions. For example, they have larger lungs than most other birds their size, and their red blood cells contain a version of hemoglobin that binds oxygen much more tightly. These geese are able to migrate more than 1609 km (1,000 mi.) in a single day. Scientists believe the geese's yearly migration is triggered by an environmental signal that allows them to miss the summer monsoon season and the worst winter storms.

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