Enzyme quantity is regulated transcriptionally, enzyme activity is allosterically controlled, and compartmentalization improves substrate accessibility.
The quantity of the enzyme, the catalytic activity, and the availability of substrates are the three main factors that regulate the activity of metabolic enzymes. It has been discovered that acetylation has a role in each of the three ways that metabolic enzymes are controlled. Regulation of metabolic pathways entails controlling an enzyme's responsiveness to signals by raising or lowering it. Control is keeping an eye on how these variations in an enzyme's activity affect the pathway's overall speed.
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