Enzymes called topoisomerases are essential for many fundamental elements of brain activity. Their major functions—cleaving DNA strands to relieve torsional stress or untangling replicating DNA—provide crucial biological controls during transcription and replication.
What part does the topoisomerase enzyme play in DNA replication? easing tension in the DNA that has been created before the replication fork due to the double helix's unwinding (Topoisomerases are enzymes involved in the over- or under-winding of DNA.
A group of enzymes known as topoisomerases modify the way double-stranded DNA gets supercoiled. (Dna supercoils by coiling up like a telephone cable, shortening the molecule.)
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