Goblet cells are required to produce the thick coating of mucus that covers the intestinal epithelium and protects it from peptic digestion and chemical damage. They can be found in the majority of the large intestine as well as the small intestine.
The gastrointestinal (GI) tract's goblet cells produce and secrete mucins, which are necessary for the creation and maintenance of a protective mucus layer. The intestinal epithelium is completely covered by this thick mucus layer.
By synthesizing and secreting high-molecular-weight glycoproteins known as mucins, goblet cells, which are found along the entire length of the small and large intestine, are in charge of producing and maintaining the protective mucus layer.
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