The skin is made up of a thick network of blood vessels and a thin membrane tissue that is quite permeable to water. The breathing gases can easily diffuse down their gradients between the blood vessels and the surroundings thanks to the thin membrane skin.
A good respiratory surface should have a sizable surface area, moist and thin walls, and be in contact with numerous blood capillaries in order to facilitate easy gas exchange or diffusion.
The gases must be allowed to dissolve and diffuse across cell membranes by maintaining moisture on the respiratory surface.
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