Respuesta :
A client taking probenecid, a uricosuric agent is having renal excretion and have prolonged effect.
What is probenecid?
Gout and gouty arthritis are prevented with the use of this drug. A sudden or severe gout attack won't be treated by it, and it might even get worse. Probenecid is a member of the uricosuric drug subclass. It reduces high uric acid levels in your body by assisting the kidneys in excreting uric acid. Gout may develop when uric acid levels are too high because crystals may accumulate in the joints. Your kidneys might benefit from lowering uric acid levels. Certain antibiotics may be administered along with benecid (such as penicillins). It raises the amount of antibiotic in the circulation, improving how well the antibiotic functions. Children under 2 years old shouldn't use probenecid.
Many medications are inhibited from leaving the body through the kidneys, which raises the concentration of other drugs and lengthens their effects. The initial treatments for gout sufferers' hyperuricemia were uricosuric medications. Any medication that, regardless of the mechanism through which it works, increases the renal excretion of uric acid may be referred to as a uricosuric medicine. Since salicylates have a contradictory effect on the kidneys' processing of uric acid—reducing renal excretion at low doses and increasing renal excretion at high doses—they were the first medications used to treat hyperuricemia associated with gout.
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