true a liver cell and a muscle cell will have different patterns of methylation and acetylation.
What distinguishes a liver cell from a skin or muscle cell, then? The way each cell uses its genome holds the key to the solution. In other words, cellular morphology (form) and function are determined by the specific combination of genes that are turned on (expressed) or turned off (repressed).
The identical genes will not be transcribed by liver cells and muscle cells. When they do, They would have the exact same morphological makeup and execute the exact same job. The main way that different genes and transcription rates contribute to cell differentiation is through their respective levels of transcription.
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