Injury to the endothelial cells that line the artery walls leads to the development of atherosclerosis.
The arteries become thicker or harder due to atherosclerosis. It is brought on by a buildup of plaque in the artery's inner lining. As plaque accumulates in the arteries, the arterial walls stiffen and thicken. Atherosclerosis is a chronic, slow-moving condition that can develop as early as childhood. It can, however, proceed along quickly. It is unclear exactly how or what causes atherosclerosis to develop. However, the inner of the artery's walls gradually thickens or accumulates plaque as a result of inflammation. The important body organs and extremities receive less blood and oxygen as a result.
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