which proteins facilitate the formation of loop domains to increase the compaction of the 30-nm fiber in eukaryotic cells?

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22-11-2022
Biology

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which proteins facilitate the formation of loop domains to increase the compaction of the 30-nm fiber in eukaryotic cells?

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charithran8975 charithran8975 · Answer 1 · 2022-11-25T00:52:22+01:00

CCCTC binding factor (CTCF) and SMC protein facilitate the formation of loop domains to increase the compaction of the 30-nm fiber in eukaryotic cells.

The zinc finger protein known as CCCTC-binding factor (CTCF) is very conserved and is well recognized for its role as a transcription factor. It can operate as an insulator protein, a repressor, or an activator of transcription, preventing communication between enhancers and promoters in eukaryotic cells.

SMC proteins work in both somatic and meiotic cells and are involved in chromosomal condensation, sister-chromatid cohesion, DNA repair and recombination, and gene dosage adjustment in eukaryotic cells.

To learn more about SMC proteins click here,

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