Respuesta :
More than half of the population has the central skin pigmentation. The lightest and the darkest skin pigmentations are equally common in the population.
Skin, hair, and eye pigmentation differs between and among human populations. Many candidate gene and numerous genome-wide association studies have sought to identify the genes and alleles responsible for this variation (GWAS). Up until now, the majority of GWAS for pigmentary features have relied on categorical scales and subjective phenotypes.
However, the color of the skin, hair, and eyes varies constantly. Here, we aim to identify the genetic basis of the quantitative variance in these qualities and to characterize it objectively and properly. Reflectance or digital spectroscopy were used to evaluate the skin, hair, and eye colors of Europeans from Ireland, Poland, Italy, and Portugal. 176 women participated in a GWAS across 313,763 SNP sites for the three quantitative pigmentation traits.
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