The Eukaryotic Chromosome Can Regulate TranscriptionBinding of basal factors and RNA polymerase to the promoter region results in a basal level of transcription gene.
Transcription of chromosome in eukaryotic:
- Unlike bacterial RNA polymerase, the primary RNA polymerase in eukaryotes like humans does not directly attach to promoters.
- Instead, basal (general) transcription factors, which are support proteins, first bind to the promoter, assisting your cells' RNA polymerase in establishing a foothold on the DNA.
- Only with the assistance of proteins referred to as basal (general) transcription factors can RNA polymerase bind to the promoter.
- They are a component of the essential transcriptional tool kit that every cell needs in order to transcribe any gene.
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