Aldosterone promotes sodium reabsorption in the kidneys.
Aldosterone is a mineralocorticoid hormone produced in the adrenal cortex's zona glomerulosa that influences water and salt regulation in the body. The adrenal cortex produces steroid hormones (the outer layer of the adrenal gland). It regulates the water and salt balance in the kidney by keeping sodium in and releasing potassium from the body. Excess aldosterone can result in high blood pressure and fluid buildup in body tissues.
The kidney's sodium reabsorption and potassium secretion are both increased by aldosterone. It primarily affects sodium and potassium balance by binding to the mineralocorticoid receptor (MCR) in the kidney's distal convoluted tubule, connecting segment, and cortical collecting duct.
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