A newborn infant presents with a diagnosis of congenital hypothyroidism. Which of the following findings is associated with congenital hypothyroidism? Select all that apply.
Hoarse cry
Open posterior fontanel
Closed cranial sutures
Hypertonia
Enlarged tongue
Hoarse cry
Open posterior fontanel
Enlarged tongue

Congenital hypothyroidism (CHT) is a condition resulting from the absence or underdevelopment (underdevelopment) of the thyroid gland, or a disorder of thyroid hormones that occurs but does not produce thyroid hormone because of a "production band problem" (abnormal hormone production). It cannot be produced. The most common cause worldwide is iodine deficiency in the diet of mothers and affected infants. Iodine is an essential requirement for the production of thyroid hormones. Genetic causes account for about 15-20% of cases of congenital hypothyroidism.

Early signs of congenital hypothyroidism in babies include:

Jaundice (yellowing of the skin and eyes)
Sleep longer or more often than usual
Constipation.
Large soft spot (fontanelle) on the head.
Large swollen tongue.
Weak (“flabby”) muscle tone.
Swelling around the eyes. Poor or slow growth.

Congenital hypothyroidism is treated by administering thyroid hormone in the form of tablets called levothyroxine. Many children require lifelong treatment. Levothyroxine should be crushed and mixed with a small amount of water, formula or breast milk using a dropper or syringe once daily.

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