All of their daughters will either have haemophilia or show symptoms of it.
A mutation or change in one of the genes, which codes for the proteins that form the clotting factor necessary for a blood clot, results in hemophilia. The clotting protein may no longer exist or function improperly as a result of this change or mutation. On the X chromosome are these genes.
Hemophilia A is brought on by changes in the FVIII gene. Hemophilia B is brought on by FIX gene mutations. The process of blood clotting depends heavily on the proteins produced by these genes. Mutations in either gene prevent clots from forming in the event of an injury, resulting in excessive bleeding that may be challenging to stop.
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