Which model and explanation best represents the semiconservative nature of dna replication?.

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24-11-2022
Biology

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Which model and explanation best represents the semiconservative nature of dna replication?.

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NomulaHarsh NomulaHarsh · Answer 1 · 2022-11-29T23:13:38+01:00

Meselson and Stahl experiment best explains the semi conservative mode of DNA replication.

What is the Meselson and Stahl experiment?

Replication is the process of making copies, i.e., duplication.

Meselson and Stahl experiment was the experimental proof for semiconservative mode of DNA replication.

Matthew Meselson and franklin Stahl conducted an experiment in 1958 on E.coli to study DNA replication.

Meselson and stahl took two isotopes of nitrogen (N14 and N15). They cultured E.coli in medium containing the N15 isotope for many generations. So the N15 was incorporated into the bacterial DNA, as a result. Then they used the N14 isotope. After regulars intervals of time, they checked density of DNA.

The first sample with N15 (after 20 mins) had bacterial DNA with intermediate density. The second sample with N14 (after 40 mins) had intermediate and light density DNAs.

Based off their observations, Meselson and Stahl concluded that DNA can replicate semi conservatively.

Therefore, Meselson and Stahl experiment best explains the semi conservative mode of DNA replication.

Learn more about Meselson and Stahl experiment here: https://brainly.com/question/14641731

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