how did you know that paclitaxel was inhibiting cell division? what method of observation was used and how did you interpret the images to come to your conclusion that paclitaxel was inhibiting cell division?

Paclitaxel (PTX), also known by the brand name Taxol, is a chemotherapy medication used to treat a variety of cancers. Ovarian cancer, oesophagal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer are all examples. It is given via intravenous injection. There is also a formulation that is albumin-bound. Hair loss, bone marrow suppression, numbness, allergic reactions, muscle pains, and diarrhoea are all common side effects. Heart problems, an increased risk of infection, and lung inflammation are among the other serious side effects. There are concerns that using it during pregnancy could result in birth defects. Paclitaxel belongs to the taxane class of drugs. It works by interfering with microtubule function during cell division.

When paclitaxel binds to microtubules, it effectively freezes them in place, preventing chromosome separation during cell division. Paclitaxel inhibits mitotic cell progression to the G1 phase by interfering with spindle formation while having no effect on other microtubule functions during anaphase and telophase.

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