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The typical maintenance dose for dantrolene sodium for the treatment of spasticity is 25-100 mg per day, divided into two to four doses.
What is Dantrolene sodium?
Dantrolene sodium (INN, trade name Dantrium) is a postsynaptic muscle relaxant that works by decreasing the release of calcium from the sarcoplasmic reticulum of skeletal muscle cells. It is used to treat muscle spasticity caused by neurological disorders, such as spinal cord injury, stroke, multiple sclerosis, and cerebral palsy. It is also used as an adjunct in the treatment of malignant hyperthermia.
The dose may be adjusted according to the patient's response to the medication.
What is Spasticity?
Spasticity is a condition in which certain muscles in the body contract and become tight, making movement difficult and sometimes painful. It is usually caused by damage to the central nervous system, such as a stroke or traumatic brain injury. Symptoms of spasticity can include stiffness, tightness, involuntary muscle spasms, and difficulty controlling the affected limb. Treatment for spasticity usually involves physical therapy, medications, exercises, and sometimes surgery.
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