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they will not be able to cross the cell membrane because osmosis

A molecule may not be able to pass into or out of a cell because it may be a large uncharged polar molecule or a charged molecule that cannot diffuse through the plasma membrane.

What is a plasma membrane?

It is a selectively permeable membrane composed of a phospholipid bilayer with proteins embedded in it.

Which molecules can and can not cross through the plasma membrane?

Small polar molecules and hydrophobic molecules can permeate across the lipid layer of the plasma membrane, while ions and big polar molecules cannot.

How do ions and large polar molecules cross the membrane?

Ions and big polar molecules can move passively or actively through the membrane due to integral membrane proteins.

What are the essential aspects that determine whether a molecule will pass through a membrane that is selectively permeable?

The ability of a molecule to diffuse through a plasma membrane is primarily influenced by three factors: size, charge, and concentration.

What would happen to the cell if all molecules were allowed to enter and exit the cell at will?

If nothing distinguished them, eventually there would be no distinction between a cell and its surroundings, and there would be no life.

To learn more about molecule and plasma membrane here,

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