Which of the following statements is true regarding the influence of population size and density on health care institutions?

A) Population size has no impact on the number and size of health care institutions.
B) Population density has no impact on the number and size of health care institutions.
C) Both population size and density have a significant influence on the number and size of health care institutions.
D) Neither population size nor density have any influence on the number and size of health care institutions.